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(20023, 821, 'sections_2_content', '<div id=\"gram-negative-bacteriocins\">\r\n  \r\n  <div class=\"gg-japanese-laurel abx-white-text text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 anim-hidden fade-in-up\">\r\n      <h2 class=\"fw-900\">Gram Negative Bacteriocins</h2>\r\n      <p style=\"line-height:2; font-size:1.4rem;\">Bacteriocins from Gram negative bacteria are broadly classified into 3 types based on their size as:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n\r\n      <div class=\"row\">\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim hidden fade-in-left\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/09/2a.-Peptide-Bacteriocins.jpg.jpg\" alt=\"peptide-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Peptide Bacteriocins</h3>\r\n          <p>Peptide Bacteriocins like microcins of less than 10 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-up\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/09/2b.-Colicins-Like-Bacteriocins.jpg-e1600372580990.jpg\" alt=\"colicin-like-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Colicin-Like Bacteriocins (CLB)</h3>\r\n          <p>Colicin-Like Bacteriocins (CLB) of 25 – 80 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-right\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"https://via.placeholder.com/150x150?text=Image+Goes+Here\" alt=\"tailocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Tailocins</h3>\r\n          <p>Tailocins which are high molecular size bacteriocins that resemble the tail structures of bacteriophages.</p>\r\n        </div>\r\n        \r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n   <div id=\"how-and-mechanisms\" class=\"px-0 py-0\" style=\"border-top:solid 8px var(--gg-calypso);\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 col-md-6 abx-white py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-calypso-text fw-900 anim-hidden fade-in-left\">How Does It Work?</h2>\r\n        	<p class=\"gg-calypso-text anim-hidden fade-in-left\" style=\"font-size:1.4rem; line-height:2;\">The CLBs entry into the bacterial cell is mediated through its interaction with cell-surface receptors, and thus conferring both specificity and selectivity. The Bacteriocin producing bacterium is protected from its own action by an immunity protein co-expressed with it.</p>\r\n        </div>\r\n      </div>\r\n      <div class=\"col-12 col-md-6 gg-light py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-japanese-laurel-text fw-900 anim-hidden fade-in-right\">Mechanism of Action</h2>\r\n        	<p class=\"gg-japanese-laurel-text anim-hidden fade-in-right\" style=\"font-size:1.4rem; line-height:2;\">The mechanism of killing is through multiple modes such as cell wall damage, cell membrane damage, interfering in metabolic pathways, and DNase or RNase activities.</p>\r\n        </div>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages-header\" class=\"gg-calypso text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n    	<h2 class=\"fw-900 abx-white-text anim-hidden fade-in-up\">Advantages of Bacteriocins</h2>\r\n    	<p class=\"abx-white-text anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins offer several advantages over antibiotics making them attractive starting points for developing anti-bacterial agents:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages\" class=\"gg-light\">\r\n   <div class=\"centerize ctz-md px-3 py-5\">\r\n    \r\n    <ul class=\"fa-ul\">\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Specific</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Their specificity offers a targeted approach and kills only the target pathogen, without damaging the commensal human microbiota or microbiome.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Resistance Development</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The Bacteriocins have a unique mode of action and hence there is no primed resistance in the bacterial community.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Selective</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins enter the bacterial cell through specific receptors which are absent on eukaryotic cells and hence are very selective agents.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Modular Architecture</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The colicin like bacteriocins (CLB) have modular domain structure that can be engineered to generate new bacteriocins with enhanced functionalities like activity/stability.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Low Toxicity</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">For generations the commensal bacteria in human body has been employing the bacteriocins to ward off invasions by pathogenic bacteria, hence natural bacteriocins can be expected to be safe to Humans.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Synergy</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The potency of bacteriocin can further be enhanced by combining them with standard of care antibiotics.</p>\r\n      </li>\r\n      \r\n    </ul>\r\n  \r\n</div>'),
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(20061, 823, 'sections_1_content', '<div id=\"protein-antibiotic-technology\" class=\"gg-calypso\">\r\n	<div class=\"centerize ctz-lg px-3 py-5 text-center anim-hidden fade-in-up\">\r\n        <h2 class=\"abx-white-text fw-900\">What are Bacteriocins?</h2>\r\n		<p class=\"abx-white-text\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins are a diverse family of protein molecules produced by many Gram positive and Gram negative bacteria with antibacterial activity. Bacteria produce these bacteriocins to eliminate competition from other closely related bacteria to eliminate competition. Bacteriocins are a unique family of naturally occurring antibacterial proteins that can be developed as potent antibiotics.</p>\r\n	</div>\r\n</div>\r\n      	\r\n      \r\n\r\n'),
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(20083, 823, 'sections_2_admin_title', 'Gram Negative Bacteriocins'),
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(20087, 823, 'sections_2_content', '<div id=\"gram-negative-bacteriocins\">\r\n  \r\n  <div class=\"gg-japanese-laurel abx-white-text text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 anim-hidden fade-in-up\">\r\n      <h2 class=\"fw-900\">Gram Negative Bacteriocins</h2>\r\n      <p style=\"line-height:2; font-size:1.4rem;\">Bacteriocins from Gram negative bacteria are broadly classified into 3 types based on their size as:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n\r\n      <div class=\"row\">\r\n        <!-- /wp-content/uploads/2020/09/2a.-Peptide-Bacteriocins.jpg.jpg -->\r\n        <div class=\"col-12 col-md-4 text-center anim hidden fade-in-left\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/09/3a.-Bacteriocin-Models-for-website-1.jpg\" alt=\"peptide-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Peptide Bacteriocins</h3>\r\n          <p>Peptide Bacteriocins like microcins of less than 10 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-up\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/09/2b.-Colicins-Like-Bacteriocins.jpg-e1600372580990.jpg\" alt=\"colicin-like-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Colicin-Like Bacteriocins (CLB)</h3>\r\n          <p>Colicin-Like Bacteriocins (CLB) of 25 – 80 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-right\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/uploads/2020/10/Lambda-Ur_Tail_model-scaled.jpg\" alt=\"tailocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Tailocins</h3>\r\n          <p>Tailocins which are high molecular size bacteriocins that resemble the tail structures of bacteriophages.</p>\r\n        </div>\r\n        \r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n   <div id=\"how-and-mechanisms\" class=\"px-0 py-0\" style=\"border-top:solid 8px var(--gg-calypso);\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 col-md-6 abx-white py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-calypso-text fw-900 anim-hidden fade-in-left\">How Does It Work?</h2>\r\n        	<p class=\"gg-calypso-text anim-hidden fade-in-left\" style=\"font-size:1.4rem; line-height:2;\">The CLBs entry into the bacterial cell is mediated through its interaction with cell-surface receptors, and thus conferring both specificity and selectivity. The Bacteriocin producing bacterium is protected from its own action by an immunity protein co-expressed with it.</p>\r\n        </div>\r\n      </div>\r\n      <div class=\"col-12 col-md-6 gg-light py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-japanese-laurel-text fw-900 anim-hidden fade-in-right\">Mechanism of Action</h2>\r\n        	<p class=\"gg-japanese-laurel-text anim-hidden fade-in-right\" style=\"font-size:1.4rem; line-height:2;\">The mechanism of killing is through multiple modes such as cell wall damage, cell membrane damage, interfering in metabolic pathways, and DNase or RNase activities.</p>\r\n        </div>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages-header\" class=\"gg-calypso text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n    	<h2 class=\"fw-900 abx-white-text anim-hidden fade-in-up\">Advantages of Bacteriocins</h2>\r\n    	<p class=\"abx-white-text anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins offer several advantages over antibiotics making them attractive starting points for developing anti-bacterial agents:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages\" class=\"gg-light\">\r\n   <div class=\"centerize ctz-md px-3 py-5\">\r\n    \r\n    <ul class=\"fa-ul\">\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Specific</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Their specificity offers a targeted approach and kills only the target pathogen, without damaging the commensal human microbiota or microbiome.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Resistance Development</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The Bacteriocins have a unique mode of action and hence there is no primed resistance in the bacterial community.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Selective</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins enter the bacterial cell through specific receptors which are absent on eukaryotic cells and hence are very selective agents.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Modular Architecture</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The colicin like bacteriocins (CLB) have modular domain structure that can be engineered to generate new bacteriocins with enhanced functionalities like activity/stability.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Low Toxicity</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">For generations the commensal bacteria in human body has been employing the bacteriocins to ward off invasions by pathogenic bacteria, hence natural bacteriocins can be expected to be safe to Humans.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Synergy</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The potency of bacteriocin can further be enhanced by combining them with standard of care antibiotics.</p>\r\n      </li>\r\n      \r\n    </ul>\r\n  \r\n</div>'),
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(20123, 824, 'sections_1_content', '<div id=\"ectolysins-against-gram-negative-bacteria\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 py-5 gg-calypso-text anim-hidden fade-in-up\">\r\n    <h2 class=\"fw-900 text-center mb-4\">Overcoming Gram-Negative Bacterial Detection</h2>\r\n    <p style=\"font-size:1.4rem; line-height:2;\">The development of ectolysins against Gram negative bacteria is a challenge due to the presence of an impermeable outer membrane that prevents access to the Gram negative peptidoglycan layer of the cell wall.</p>\r\n\r\n	<p style=\"font-size:1.4rem; line-height:2;\">GangaGen has successfully overcome this challenge to discover and engineer lysins with broad spectrum activity against human pathogens such as <em>Acinetobacter baumannii</em> and <em>Pseudomonas aeruginosa</em>.</p>\r\n\r\n	<p style=\"font-size:1.4rem; line-height:2;\">GangaGen\'s Gram negative ectolysins are potent in diverse <em>in vitro</em> studies including demonstrated activity in relevant biological fluids and in vivo studies. GangaGen aims to develop these ectolysins as an intravenous therapeutic for human applications.</p>\r\n  </div>\r\n</div>'),
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(20159, 825, 'sections_1_content', '<div id=\"ectolysins-against-gram-postitive-bacteria\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 py-5\">\r\n    <h2 class=\"text-center gg-japanese-laurel-text fw-900 anim-hidden fade-in-down\">Ectolysins against Staphylococcus</h2>\r\n	<p class=\"gg-calypso-text text-center anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">Ectolysin P128, GangaGen’s lead molecule is a chimeric recombinant anti-staphylococcal protein that targets both coagulase positive and coagulase negative Staphylococci.</p> \r\n    <p class=\"gg-calypso-text text-center anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">P128 has a novel mechanism of action and rapidly kills Staphylococci.</p>\r\n	<p class=\"gg-calypso-text text-center anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">It is proven to be very effective both in vitro &amp; in vivo against multidrug resistant pathogens like Methicillin Resistant <em>Staphylococcus</em> aureus (MRSA), Vancomycin Resistant <em>Staphylococcus aureus</em> (VRSA) and Daptomycin Resistant <em>Staphylococcus aureus</em> (DRSA). GangaGen has completed Phase I/IIA studies with P128 for ‘nasal decontamination of <em>S. aureus</em> from human nares.</p>	\r\n  </div>\r\n</div>\r\n\r\n<div class=\"gg-japanese-laurel gg-light-text\" style=\"border-bottom:solid 3px var(--gg-light);\">\r\n  <div class=\"centerize ctz-md text-center px-3 py-5\">\r\n    <h2 class=\"fw-900 text-center anim-hidden fade-in-down\">Ectolysins against Enterococcus</h2>\r\n	<p class=\"anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">GangaGen has used PATP to discover and engineer novel ectolysins suitable for multiple applications.</p>\r\n  </div>\r\n</div>'),
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(20221, 826, 'sections_2_content', '<div id=\"ectolysin-advantages\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 py-5\">\r\n    <div class=\"text-left mb-4\">\r\n    	<h2 class=\"fw-900 gg-calypso-text\">Advantages of Ectolysins over Antibiotics</h2>\r\n    </div>\r\n    \r\n    <ul class=\"fa-ul\">\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Rapid Action</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins are rapid acting and cleave the cell wall within a few minutes of contact against antibiotics that only need a few hours to kill the cells.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Specific</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins are very specific to the target bacterial species and hence kill only the target pathogen without affecting the microbiome or the commensal bacterial flora as compared to antibiotics which kill both the pathogens as well as the beneficial bacteria.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Mechanism of Action</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins have novel mode of action- they include enzymatic mechanisms like Muramidase, Glucosaminidase, Amidase or endopeptidase depending upon the cell wall bond targeted by the individual ectolysin.  The availability of a library of enzymatic domains offers the opportunity of protein engineering.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Bactericidal Activity Independence</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Bactericidal activity is not dependent on the metabolic stage of the cell – Ectolysins kill both actively growing as well as stationary phase cells irrespective of the metabolic state. But antibiotics act only on metabolically active cells.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Active on Biofilms</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins are active both on planktonic bacteria &amp; bacterial biofilms as against antibiotics, which act poorly on bacterial biofilms.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Low Propensity for Resistance</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins cleave essential cell wall chemical bonds, which are highly conserved and omnipresent on the bacterial cell surface; hence the propensity for the development of bacterial resistance is low.</p> \r\n    </ul>\r\n  </div>\r\n</div>\r\n\r\n'),
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(20283, 827, 'sections_1_content', '<div id=\"ectolysins-against-gram-negative-bacteria\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 py-5 gg-calypso-text anim-hidden fade-in-up\">\r\n    <h2 class=\"fw-900 text-center mb-4\">Overcoming Gram-Negative Bacterial Detection</h2>\r\n    <p style=\"font-size:1.4rem; line-height:2;\">The development of ectolysins against Gram negative bacteria is a challenge due to the presence of an impermeable outer membrane that prevents access to the Gram negative peptidoglycan layer of the cell wall.</p>\r\n\r\n	<p style=\"font-size:1.4rem; line-height:2;\">GangaGen has successfully overcome this challenge to discover and engineer lysins with broad spectrum activity against human pathogens such as <em>Acinetobacter baumannii</em> and <em>Pseudomonas aeruginosa</em>.</p>\r\n\r\n	<p style=\"font-size:1.4rem; line-height:2;\">GangaGen\'s Gram negative ectolysins are potent in diverse <em>in vitro</em> studies including demonstrated activity in relevant biological fluids and <em>in vivo</em> studies. GangaGen aims to develop these ectolysins as an intravenous therapeutic for human applications.</p>\r\n  </div>\r\n</div>'),
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(20317, 828, 'sections_1_content', '<div id=\"p128\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 py-5\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12\">\r\n        <h2 class=\"gg-japanese-laurel-text fw-900 text-center\">How Does Ectolysin P128 Work?</h2>\r\n        <p class=\"gg-japanese-laurel-text\" style=\"font-size:1.4rem; line-height:2;\">Ectolysin P128, Gangagen’s lead ectolysin is a recombinant, chimeric protein that comprises of two functionally distinct domains. The catalytic domain is a muralytic enzyme and the binding domain specifically interacts with the pentaglycine bridge connecting the D-Ala-D-Ala moieties of adjacent peptidoglycan strands. Functionally, P128 is an endopeptidase and its enzymatic action on the staphylococcal peptidoglycan results in the cleavage of the specifc peptide linkages. This leads to the degradation of the cell wall, followed by osmotic lysis and rapid death of the bacterium. P128 targets both coagulase positive and coagulase negative Staphylococci.</p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n</div>\r\n    \r\n<div id=\"mechanism-of-action\" class=\"abx-white\">\r\n  <div class=\"centerize ctz-lg px-3 pt-5\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 col-md-6 anim-hidden fade-in-left\">\r\n        <img src=\"/wp-content/uploads/2020/09/4.-P128-Mechanism-of-Action.jpg\" alt=\"p128\" />\r\n      </div>\r\n      <div class=\"col-12 col-md-6 anim-hidden fade-in-right\">\r\n        <h2 class=\"gg-japanese-laurel-text fw-900\">Mechanism of Action</h2>\r\n        <p class=\"gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">P128 has a novel mechanism of action and has been proven to be very effective both <em>in vitro</em> &amp; <em>in vivo</em> against multidrug resistant pathogens like Methicillin Resistant <em>Staphylococcus aureus</em> (MRSA), Vancomycin Resistant <em>Staphylococcus aureus</em> (VRSA) and Daptomycin Resistant <em>Staphylococcus aureus</em> (DRSA).</p> \r\n      </div>\r\n    </div>\r\n  </div>\r\n</div>\r\n    \r\n<div id=\"p128-manufacturing\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 pt-5\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 anim-hidden fade-in-up text-center\">\r\n        <h2 class=\"gg-japanese-laurel-text fw-900\">Scalable Manufacturing Process</h2>\r\n        <p class=\"gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">Gangagen has successfully developed the manufacturing process for large scale production of P128 to meet the regulatory standards for clinical studies. P128 formulated as a gel for topical use has been tested in a first-in-human clinical trial, a Phase I/IIA study directed towards treatment of nasal carriage of <em>S. aureus</em>.</p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n</div>\r\n\r\n<!-- <div id=\"p128-chart\" class=\"abx-white\">\r\n  <div class=\"px-3 py-5\">\r\n    <img class=\"anim-hidden fade-in-up\" src=\"/wp-content/uploads/2020/09/6.-P128-banner_final-scaled.jpg\" alt=\"p128-chart\" />\r\n  </div>\r\n</div> -->\r\n\r\n<!-- <div id=\"p128-quote\" style=\"padding:10% 2rem; background:linear-gradient(rgba(0,0,0,0.4),rgba(0,0,0,0.4)), url(\'/wp-content/uploads/2020/09/gangagen-007.jpg\'); background-attachment:fixed; background-size:cover; background-repeat:no-repeat;\">\r\n  <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n    <p class=\"abx-white-text fw-700 anim-hidden zoom-in\" style=\"font-size:1.4rem; line-height:2;\"><span class=\"quot\" style=\"display:block;\"><i class=\"fa fa-3x fa-quote-left\"></i></span><em>In 15 European countries more than 10% of blood-stream Staphylococcus aureus infections are caused by methicillin-resistant strains (MRSA), with several of these countries seeing resistance rates closer to 50%.</em><span class=\"quot\" style=\"display:block;\"><i class=\"fa fa-4x fa-quote-right\"></i></span></p>\r\n  </div>\r\n</div> -->\r\n\r\n<div id=\"p128-innovation\" class=\"gg-light gg-calypso-text\">\r\n  <div class=\"centerize ctz-md px-3 py-5 text-center\">\r\n     <h2 class=\"fw-900 anim-hidden fade-in-down\">P128 Clinical Trial</h2>\r\n  	 <p class=\"anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">GBPL advanced its candidate compound into human clinical trials for the decolonization of <em>Staphylococcus aureus</em> from human nares.</p>    \r\n  </div>\r\n</div>\r\n    \r\n<div id=\"p128-innovation\" class=\"gg-calypso gg-light-text\">\r\n  <div class=\"centerize ctz-md px-3 py-5 text-center\">\r\n     <h2 class=\"fw-900 anim-hidden fade-in-down\">Intravenous Treatment</h2>\r\n  	 <p class=\"anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">GBPL is also advancing Ectolysin P128 for intravenous treatment of bacteremia caused by Staphylococcus Species.</p>    \r\n  </div>\r\n</div>\r\n\r\n\r\n'),
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(20351, 829, 'sections_1_admin_title', 'Bacteriophages Overview'),
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(20355, 829, 'sections_1_content', '<div id=\"bacteriophages-overview\" class=\"gg-golden-bell abx-white-text\">\r\n  <div class=\"centerize ctz-lg px-3 py-5 text-center anim-hidden fade-in-up\">\r\n    <h2 class=\"fw-700\">What are Bacteriophages?</h2>\r\n    <p style=\"font-size:1.4rem; line-height:2;\">Bacteriophages (\"phages\" for short) are viruses that prey on bacteria only. Phages are the most ubiquitous organisms on Earth, and they abound in natural as well as in man-made environments, where ever bacteria exist.</p>\r\n	<p style=\"font-size:1.4rem; line-height:2;\">Phages can be used to control undesirable bacteria in various settings where bacteria may cause disease, contamination, disturbance or imbalance in natural microbiome.</p>\r\n    \r\n  </div>\r\n</div>\r\n\r\n<div id=\"gangagen-bacteriophages\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 pt-5 text-center anim-hidden fade-in-up\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 pb-5 anim-hidden fade-in-up text-center\">\r\n        <h2 class=\"gg-japanese-laurel-text fw-700\">GBPL\'s Phage Expertise</h2>\r\n        <p class=\"gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">GBPL’s phage expertise and core bacteriophage technology is applied towards developing safe and effective antibacterial products based on naturally-occurring phages.</p>\r\n      </div>\r\n      <!-- <div class=\"col-12 col-md-6 order-1 order-md-2 pb-5 anim-hidden fade-in-right text-center\">\r\n        <img src=\"https://via.placeholder.com/250x250/?text=GangaGen+Phage+Expertise+Image\" alt=\"gangagen-phage-expertise\" />\r\n      </div> -->\r\n    </div>\r\n  </div>\r\n</div>\r\n\r\n<!-- <div id=\"gangagen-phage-methods\" class=\"abx-white\">\r\n  <div class=\"centerize ctz-md px-3 py-5 anim-hidden fade-in-up\">\r\n    <h2 class=\"text-center gg-japanese-laurel-text fw-700\">GangaGen\'s Phage Methods</h2>\r\n    <p class=\"text-center gg-golden-bell-text\" style=\"font-size:1.4rem; line-height:2;\">Gangagen has developed methods to:</p>\r\n    <ul class=\"fa-ul\" style=\"font-size:1.4rem; line-height:1.6; width:360px; margin:0 auto;\">\r\n      <li class=\"mb-4 anim-hidden fade-in-left\"><span class=\"fa-li\"><i class=\"fa fa-check gg-japanese-laurel abx-white-text\" style=\"padding:0.4rem; border-radius:50%;\"></i></span> <span class=\"gg-calypso-text\" style=\"margin-top:5px;\">Rapidly isolate phages effective on a given species of bacteria</span></li>\r\n      <li class=\"mb-4 anim-hidden fade-in-left\"><span class=\"fa-li\"><i class=\"fa fa-check gg-japanese-laurel abx-white-text\" style=\"padding:0.4rem; border-radius:50%;\"></i></span> <span class=\"gg-calypso-text\" style=\"margin-top:5px;\">Characterize phages</span></li>\r\n      <li class=\"mb-4 anim-hidden fade-in-left\"><span class=\"fa-li\"><i class=\"fa fa-check gg-japanese-laurel abx-white-text\" style=\"padding:0.4rem; border-radius:50%;\"></i></span> <span class=\"gg-calypso-text\" style=\"margin-top:5px;\">Build effective custom cocktails against different pathogenic bacteria</span></li>\r\n    </ul>\r\n  </div>\r\n</div> -->\r\n\r\n<div id=\"gangagen-phage-library\" style=\"\r\n    background:linear-gradient(rgba(255,255,255,0.6), rgba(255,255,255,0.6)), url(\'/wp-content/uploads/2020/09/gangagen-009.jpg\'); \r\n    background-size: cover;\r\n    background-repeat: no-repeat;\r\n    background-position: center center;\r\n\">\r\n  <div class=\"centerize ctz-md px-3 text-center anim-hidden fade-in-up abx-white-text\" style=\"padding-top:12%; padding-bottom:12%; text-shadow: 0 2px 6px var(--gg-calypso);\">\r\n    <h2 class=\"fw-700 mb-3\">GangaGen Phage Library</h2>\r\n    <p class=\"mb-3\" style=\"font-size:1.4rem; line-height:2;\">GBPL’s phage technology platform includes a library of about 500 phages and a collection of more than 3,000 strains representing a diverse set of pathogens. Additionally GBPL has extensive experience in phage isolation, phage engineering, developing phage cocktails and manufacturing of phages for different applications.</p>\r\n    <p class=\"mb-3\" style=\"font-size:1.4rem; line-height:2;\">In 2007, GBPL made a strategic decision to focus it’s expertise on the use of ‘phage technology’ for novel non-human applications. These applications include: Food Safety, Veterinary, Environment, and Agriculture.</p>\r\n    <a href=\"/novel-applications\"><button class=\"gangagen-button-clear\">See Phage Applications</button></a>\r\n  </div>\r\n</div>'),
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(20391, 830, 'sections_1_content', '<div id=\"novel-applications\">\r\n  \r\n  <!-- <div class=\"gg-golden-bell\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      <h2 class=\"anim-hidden fade-in-up gg-golden-bell-text fw-900\">Novel Applications: GBPL\'s Efforts</h2>\r\n      <p class=\"abx-white-text anim-hidden fade-in-up text-center\" style=\"font-size:1.4rem; line-height:2;\">Phages can be used to control undesirable bacteria in various settings where bacteria may cause disease, contamination, disturbance or imbalance in natural microbiomes, or other problems. Gangagen has also used phages to tackle environment related challenges.</p>\r\n    </div>\r\n  </div> -->\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      \r\n      <div class=\"text-center\">\r\n        <h2 class=\"anim-hidden fade-in-up gg-golden-bell-text fw-900\">Applications in Poultry</h2>\r\n        <p class=\"anim-hidden fade-in-up gg-golden-bell-text\" style=\"font-size:1.4rem; line-height:2;\">GBPL has developed a cocktail of lytic phages to control <em>Salmonella</em> infection in chicken. The company has isolated a number of phages and identified 3 phages that are capable of killing most of the <em>Salmonella</em> isolates present in the poultry field. GBPL scientists have characterized these phages and also conducted a field trial to establish efficacy of the phage cocktail and to improve overall health and FCR (Feed Consumption Ratio) in the birds. This product is available for commercial evaluation and marketing.</p>\r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-light\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      \r\n      <div class=\"text-center\">\r\n        <h2 class=\"anim-hidden fade-in-up gg-calypso-text fw-900\">Other Areas Of Interest</h2>\r\n        <p class=\"anim-hidden fade-in-up gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">GBPL has explored the use of bacteriophages in tackling <em>Vibrio harveyi</em> infections in aquaculture industry and isolated phages that work on these bacteria. The company is open for collaborative approach to develop this as a product. In addition, GBPL has worked on isolating phages that can kill sulphate reducing bacteria responsible for corrosion of oil pipelines and establishing a method of testing them for efficacy. </p>\r\n        <p class=\"anim-hidden fade-in-up gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">Any industrial set up looking for a phage based, eco-friendly solution to combat bacterial burden, may contact us for a mutually beneficial research programs.</p>\r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-calypso abx-white-text\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n    	<h2 class=\"fw-900 anim-hidden fade-in-down animated visible fadeInDown full-visible\">For More Information:</h2>\r\n    	<div class=\"text-center\">\r\n    		<a href=\"mailto:info@gangagen\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Email</button></a>\r\n    		<a href=\"/contact\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Contact Form</button></a>\r\n    	</div>\r\n    </div>\r\n  </div>\r\n  \r\n</div>\r\n'),
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(21237, 841, 'sections_1_content', '<style>\r\n  #office-locations th, #office-locations td {border:none !important; padding:0;}\r\n  iframe {max-width:100% !important;}\r\n</style>\r\n<div id=\"office-locations\">\r\n  \r\n    <div class=\"gg-calypso abx-white-text\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n      <h2 class=\"fw-900 anim-hidden fade-in-up\">Research and Development Center<br/>GangaGen Biotechnologies Pvt. Ltd.</h2>\r\n      <h3 class=\"anim-hidden fade-in-up\">\r\n      	No 12, 5th Cross, Raghavendra Layout,<br/>\r\n        Opposite to MEI Ltd, Tumkur Road,<br/>\r\n        Yeshwanthpur, Bangalore -560022, India<br/> \r\n      </h3>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-light\">\r\n    <div class=\"centerize ctz-lg px-3 pt-5\">\r\n      <div class=\"row\">\r\n        <div class=\"col-12 col-sm-4 pb-5 text-center anim-hidden fade-in-left\">\r\n        	<a class=\"gangagen-button-calypso\" href=\"tel:+918040621300\" style=\"padding:0.4rem;\"><i class=\"fa fa-phone\"></i> +91-80-40621300</a>\r\n        </div>\r\n        <div class=\"col-12 col-sm-4 pb-5 text-center anim-hidden fade-in-up\">\r\n        	<a class=\"gangagen-button-calypso\" href=\"tel:+918040621329\" style=\"padding:0.4rem;\"><i class=\"fa fa-fax\"></i> +91-80-40621329</a>\r\n        </div>\r\n        <div class=\"col-12 col-sm-4 pb-5 text-center anim-hidden fade-in-right\">\r\n        	<a class=\"gangagen-button-calypso\" href=\"mailto:info@gangagen.com\" style=\"padding:0.4rem;\"><i class=\"fa fa-envelope\"></i> info@gangagen.com</a>\r\n        </div>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n      <div class=\"row anim-hidden fade-in-up\">\r\n        <div class=\"col-12\">\r\n          <!-- Embedded Google Map <iframe> -->\r\n          <iframe src=\"https://www.google.com/maps/embed?pb=!1m18!1m12!1m3!1d62196.688524009136!2d77.55521500337848!3d13.017002148046354!2m3!1f0!2f0!3f0!3m2!1i1024!2i768!4f13.1!3m3!1m2!1s0x3bae3d69506541f7%3A0xfe0757fd08c9f59a!2sGangagen%20Biotechnologies%20Pvt%20Ltd!5e0!3m2!1sen!2sus!4v1600048283304!5m2!1sen!2sus\" width=\"600\" height=\"450\" frameborder=\"0\" style=\"border:0;\" allowfullscreen=\"\" aria-hidden=\"false\" tabindex=\"0\"></iframe>\r\n        </div>\r\n      </div>\r\n    </div>\r\n  </div>\r\n \r\n  <!-- Hidden \r\n  <div class=\"gg-calypso\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n      <h2 class=\"fw-900 abx-white-text\">Corporate Office:</h2>\r\n    </div>\r\n  </div>\r\n\r\n  <div class=\"gg-light\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n      <div class=\"row\">\r\n        <div class=\"col-12 col-md-6 order-2 order-md-1\">\r\n          	<table class=\"table table-borderless gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\"><tbody>\r\n              <tr><td colspan=\"2\">Bactoclear Holdings Pte. Ltd</td></tr>\r\n              <tr><td colspan=\"2\">1 Robinson Road, #17-00, Aia Tower,</td></tr>\r\n              <tr><td colspan=\"2\">Singapore 04854</td></tr>\r\n            </tbody></table>\r\n        </div>\r\n        <div class=\"col-12 col-md-6 order-1 order-md-2\">\r\n          <\r\n          <iframe src=\"https://www.google.com/maps/embed?pb=!1m18!1m12!1m3!1d3988.8197875173364!2d103.84893321528233!3d1.2818915990650341!2m3!1f0!2f0!3f0!3m2!1i1024!2i768!4f13.1!3m3!1m2!1s0x31da197d9f6c9b21%3A0xa9404ebb62830a8c!2sAIA%20Tower!5e0!3m2!1sen!2sus!4v1600048353502!5m2!1sen!2sus\" width=\"600\" height=\"450\" frameborder=\"0\" style=\"border:0;\" allowfullscreen=\"\" aria-hidden=\"false\" tabindex=\"0\"></iframe>\r\n        </div>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  -->\r\n</div>'),
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(21273, 843, 'sections_1_content', '<div id=\"gangagen-mission\" class=\"gg-japanese-laurel\">\r\n  <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n    <h2 class=\"fw-700 abx-white-text anim-hidden fade-in\">Our mission is to discover, design and develop highly specific and safe Protein Antiobiotics for treating bacterial infections.</h2>\r\n  </div>\r\n</div>\r\n\r\n<div id=\"gangagen-overview\">\r\n\r\n  	<div class=\"abx-white\" style=\"background:linear-gradient(rgba(0,0,0,0.4),rgba(0,0,0,0.4), url(\'/wp-content/uploads/2020/09/gangagen-facility-05.jpg\');\">\r\n        <div class=\"centerize ctz-lg px-3 py-5\">\r\n           <div class=\"row\">\r\n              <div class=\"\">\r\n                  <div class=\"content-group mb-4 anim-hidden fade-in-left\">\r\n                    <h2 class=\"text-center abx-white-text fw-700\">Overview</h2>\r\n                    <p class=\"text-left abx-white-text\" style=\"font-size:1.4rem; line-height:2;\">GangaGen Biotechnologies Private Limited, India (GBPL), is a biologics company specialized in discovering, designing and developing novel therapies for treating serious bacterial infections. GangaGen advanced it’s candidate compound into human clinical trials for the decolonization of Methicillin Resistant <em>Staphylococcus aureus</em> from human nares in 2015.</p>\r\n                  </div>\r\n              </div>\r\n           </div>\r\n        </div>\r\n    </div>\r\n  \r\n    <div class=\"gg-light\">\r\n        <div class=\"centerize ctz-lg px-3 py-5\">\r\n           <div class=\"row\">\r\n                <div class=\"col-12 col-md-6 py-3 text-center\">\r\n                    <div class=\"content-group mb-4 anim-hidden fade-in-left\">\r\n                      <img src=\"/wp-content/uploads/2020/09/gangagen-beginninigs-e1600361407146.jpg\" alt=\"gangagen-image\" />\r\n                    </div>\r\n                </div>\r\n             	<div class=\"col-12 col-md-6 py-2\">\r\n                    <div class=\"content-group mb-4 anim-hidden fade-in-right\">\r\n                      <h2 class=\"text-center gg-japanese-laurel-text fw-700\">GBPL\'s Beginnings</h2>\r\n                      <p class=\"text-left\" style=\"font-size:1.4rem; line-height:2;\">GBPL was founded and registered in India in 2000 by Prof J. Ramachandran and became a subsidiary of GangaGen Inc., a Delaware company in the US in 2001. The assets of GangaGen Inc. were transferred to Bactoclear Holdings in 2019.</p>\r\n                    </div>\r\n                </div>\r\n            </div>\r\n        </div>\r\n  	</div>\r\n  \r\n    <div class=\"abx-white\">\r\n        <div class=\"centerize ctz-lg px-3 py-5\">\r\n           <div class=\"row\">\r\n                <div class=\"col-12 py-2 text-center\">\r\n                    <div class=\"content-group mb-4 anim-hidden fade-in-up\">\r\n                      <h2 class=\"text-center gg-japanese-laurel-text fw-700\">GBPL Ownership</h2>\r\n                      <p class=\"text-left\" style=\"font-size:1.4rem; line-height:2;\">GBPL is a wholly owned subsidiary of <span class=\"gg-japanese-laurel-text fw-900\">Bactoclear Holdings Pte. Ltd., a Singapore company</span>. The board of Bactoclear Holdings is made up of investors from different parts of the world, committed to make a difference in tackling antimicrobial resistance.</p>\r\n                    </div>\r\n                </div>\r\n            </div>\r\n        </div>\r\n  	</div>\r\n  \r\n  	<div class=\"gg-japanese-laurel abx-white-text text-center\" style=\"border-bottom:solid 3px var(--gg-light);\">\r\n      <div class=\"centerize ctz-lg px-3 py-5\">\r\n      	<h2 class=\"anim-hidden fade-in-up\">GangaGen\'s Research Focus</h2>\r\n      	<p class=\"anim-hidden fade-in-up text-left\" style=\"font-size:1.4rem; line-height:2;\">GangaGen’s expertise towards designing novel Protein Antibiotics is based on its proprietary technology platforms</p>\r\n      </div>\r\n    </div>\r\n  \r\n</div>'),
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(22133, 855, 'sections_2_content', '<div id=\"gram-negative-bacteriocins\">\r\n  \r\n  <div class=\"gg-japanese-laurel abx-white-text text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 anim-hidden fade-in-up\">\r\n      <h2 class=\"fw-900\">Gram Negative Bacteriocins</h2>\r\n      <p style=\"line-height:2; font-size:1.4rem;\">Bacteriocins from Gram negative bacteria are broadly classified into 3 types based on their size as:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n\r\n      <div class=\"row\">\r\n        <!-- /wp-content/uploads/2020/09/2a.-Peptide-Bacteriocins.jpg.jpg -->\r\n        <div class=\"col-12 col-md-4 text-center anim hidden fade-in-left\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/10/2a-Peptide-Bacteriocins.jpg.jpg\" alt=\"peptide-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Peptide Bacteriocins</h3>\r\n          <p>Peptide Bacteriocins like microcins of less than 10 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-up\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/09/2b.-Colicins-Like-Bacteriocins.jpg-e1600372580990.jpg\" alt=\"colicin-like-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Colicin-Like Bacteriocins (CLB)</h3>\r\n          <p>Colicin-Like Bacteriocins (CLB) of 25 – 80 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-right\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/10/Lambda-Ur_Tail_model-scaled.jpg\" alt=\"tailocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Tailocins</h3>\r\n          <p>Tailocins which are high molecular size bacteriocins that resemble the tail structures of bacteriophages.</p>\r\n        </div>\r\n        \r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n   <div id=\"how-and-mechanisms\" class=\"px-0 py-0\" style=\"border-top:solid 8px var(--gg-calypso);\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 col-md-6 abx-white py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-calypso-text fw-900 anim-hidden fade-in-left\">How Does It Work?</h2>\r\n        	<p class=\"gg-calypso-text anim-hidden fade-in-left\" style=\"font-size:1.4rem; line-height:2;\">The CLBs entry into the bacterial cell is mediated through its interaction with cell-surface receptors, and thus conferring both specificity and selectivity. The Bacteriocin producing bacterium is protected from its own action by an immunity protein co-expressed with it.</p>\r\n        </div>\r\n      </div>\r\n      <div class=\"col-12 col-md-6 gg-light py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-japanese-laurel-text fw-900 anim-hidden fade-in-right\">Mechanism of Action</h2>\r\n        	<p class=\"gg-japanese-laurel-text anim-hidden fade-in-right\" style=\"font-size:1.4rem; line-height:2;\">The mechanism of killing is through multiple modes such as cell wall damage, cell membrane damage, interfering in metabolic pathways, and DNase or RNase activities.</p>\r\n        </div>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages-header\" class=\"gg-calypso text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n    	<h2 class=\"fw-900 abx-white-text anim-hidden fade-in-up\">Advantages of Bacteriocins</h2>\r\n    	<p class=\"abx-white-text anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins offer several advantages over antibiotics making them attractive starting points for developing anti-bacterial agents:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages\" class=\"gg-light\">\r\n   <div class=\"centerize ctz-md px-3 py-5\">\r\n    \r\n    <ul class=\"fa-ul\">\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Specific</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Their specificity offers a targeted approach and kills only the target pathogen, without damaging the commensal human microbiota or microbiome.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Resistance Development</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The Bacteriocins have a unique mode of action and hence there is no primed resistance in the bacterial community.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Selective</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins enter the bacterial cell through specific receptors which are absent on eukaryotic cells and hence are very selective agents.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Modular Architecture</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The colicin like bacteriocins (CLB) have modular domain structure that can be engineered to generate new bacteriocins with enhanced functionalities like activity/stability.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Low Toxicity</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">For generations the commensal bacteria in human body has been employing the bacteriocins to ward off invasions by pathogenic bacteria, hence natural bacteriocins can be expected to be safe to Humans.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Synergy</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The potency of bacteriocin can further be enhanced by combining them with standard of care antibiotics.</p>\r\n      </li>\r\n      \r\n    </ul>\r\n  \r\n</div>\r\n    \r\n<div class=\"abx-white\">\r\n   <div class=\"centerize ctz-md px-3 py-5 text-center anim-hidden fade-in-up\">\r\n     <a href=\"https://carb-x.org/\" target=\"_blank\">\r\n       <img src=\"/wp-content/uploads/2020/10/CARB-X_logo.jpg\" alt=\"carb-x-logo\" style=\"width:300px; margin:0 auto; display:inherit;\" />\r\n     </a>\r\n   </div>\r\n</div>'),
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(22400, 868, 'sections_2_content', '<div id=\"protein-antibiotic-classes\">\r\n  \r\n  <div class=\"gg-japanese-laurel abx-white-text\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 text-center anim-hidden fade-in\">\r\n      <h2>Protein Antibacterial Classes</h2>\r\n      <p>Protein Antibacterials being researched at GangaGen belong to 2 major classes:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      <div class=\"row\">\r\n\r\n        <div class=\"col-12 col-md-6 text-center anim-hidden fade-in-left\">\r\n			<img class=\"mb-4\" src=\"/wp-content/uploads/2020/09/1a.-Bacteriocins.jpg.jpg\" style=\"height:160px;\" alt=\"gangagen-bacteriocins\" />\r\n          	<h3 class=\"mb-4 gg-japanese-laurel-text\">Bacteriocins</h3>\r\n            <a href=\"/bacteriocins\"><button class=\"gangagen-button\">Learn More</button></a>\r\n        </div>\r\n\r\n        <div class=\"col-12 col-md-6 text-center anim-hidden fade-in-right\">\r\n			<img class=\"mb-4\" src=\"/wp-content/uploads/2020/09/1b.Lysins.jpg-e1600360004397.jpg\" style=\"height:160px;\" alt=\"gangagen-lysins\" />\r\n          	<h3 class=\"mb-4 gg-japanese-laurel-text\">Lysins</h3>\r\n            <a href=\"/lysins\"><button class=\"gangagen-button\">Learn More</button></a>\r\n        </div>\r\n\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-md px-3 py-5 text-center anim-hidden fade-in-up\">\r\n      <a href=\"https://carb-x.org/\" target=\"_blank\">\r\n        <img src=\"/wp-content/uploads/2020/10/CARB-X_logo.jpg\" alt=\"carb-x-logo\" style=\"width:300px; margin:0 auto; display:inherit;\" />\r\n      </a>\r\n    </div>\r\n  </div>\r\n</div>'),
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(22436, 870, 'sections_1_content', '<div id=\"protein-antibiotic-technology\" class=\"gg-calypso\">\r\n	<div class=\"centerize ctz-lg px-3 py-5 text-center anim-hidden fade-in-up\">\r\n        <h2 class=\"abx-white-text fw-900\">What are Bacteriocins?</h2>\r\n		<p class=\"abx-white-text\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins are a diverse family of protein molecules produced by many Gram positive and Gram negative bacteria with antibacterial activity. Bacteria produce these bacteriocins to eliminate competition from other closely related bacteria to eliminate competition. Bacteriocins are a unique family of naturally occurring antibacterial proteins that can be developed as potent antibiotics.</p>\r\n	</div>\r\n</div>\r\n      	\r\n      \r\n\r\n'),
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(22458, 870, 'sections_2_admin_title', 'Gram Negative Bacteriocins'),
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(22462, 870, 'sections_2_content', '<div id=\"gram-negative-bacteriocins\">\r\n  \r\n  <div class=\"gg-japanese-laurel abx-white-text text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 anim-hidden fade-in-up\">\r\n      <h2 class=\"fw-900\">Gram Negative Bacteriocins</h2>\r\n      <p style=\"line-height:2; font-size:1.4rem;\">Bacteriocins from Gram negative bacteria are broadly classified into 3 types based on their size as:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n\r\n      <div class=\"row\">\r\n        <!-- /wp-content/uploads/2020/09/2a.-Peptide-Bacteriocins.jpg.jpg -->\r\n        <div class=\"col-12 col-md-4 text-center anim hidden fade-in-left\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/10/2a-Peptide-Bacteriocins.jpg.jpg\" alt=\"peptide-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Peptide Bacteriocins</h3>\r\n          <p>Peptide Bacteriocins like microcins of less than 10 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-up\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/09/2b.-Colicins-Like-Bacteriocins.jpg-e1600372580990.jpg\" alt=\"colicin-like-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Colicin-Like Bacteriocins (CLB)</h3>\r\n          <p>Colicin-Like Bacteriocins (CLB) of 25 – 80 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-right\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/10/Lambda-Ur_Tail_model-scaled.jpg\" alt=\"tailocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Tailocins</h3>\r\n          <p>Tailocins which are high molecular size bacteriocins that resemble the tail structures of bacteriophages.</p>\r\n        </div>\r\n        \r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n   <div id=\"how-and-mechanisms\" class=\"px-0 py-0\" style=\"border-top:solid 8px var(--gg-calypso);\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 col-md-6 abx-white py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-calypso-text fw-900 anim-hidden fade-in-left\">How Does It Work?</h2>\r\n        	<p class=\"gg-calypso-text anim-hidden fade-in-left\" style=\"font-size:1.4rem; line-height:2;\">The CLBs entry into the bacterial cell is mediated through its interaction with cell-surface receptors, and thus conferring both specificity and selectivity. The Bacteriocin producing bacterium is protected from its own action by an immunity protein co-expressed with it.</p>\r\n        </div>\r\n      </div>\r\n      <div class=\"col-12 col-md-6 gg-light py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-japanese-laurel-text fw-900 anim-hidden fade-in-right\">Mechanism of Action</h2>\r\n        	<p class=\"gg-japanese-laurel-text anim-hidden fade-in-right\" style=\"font-size:1.4rem; line-height:2;\">The mechanism of killing is through multiple modes such as cell wall damage, cell membrane damage, interfering in metabolic pathways, and DNase or RNase activities.</p>\r\n        </div>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages-header\" class=\"gg-calypso text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n    	<h2 class=\"fw-900 abx-white-text anim-hidden fade-in-up\">Advantages of Bacteriocins</h2>\r\n    	<p class=\"abx-white-text anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins offer several advantages over antibiotics making them attractive starting points for developing anti-bacterial agents:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages\" class=\"gg-light\">\r\n   <div class=\"centerize ctz-md px-3 py-5\">\r\n    \r\n    <ul class=\"fa-ul\">\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Specific</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Their specificity offers a targeted approach and kills only the target pathogen, without damaging the commensal human microbiota or microbiome.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Resistance Development</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The Bacteriocins have a unique mode of action and hence there is no primed resistance in the bacterial community.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Selective</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins enter the bacterial cell through specific receptors which are absent on eukaryotic cells and hence are very selective agents.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Modular Architecture</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The colicin like bacteriocins (CLB) have modular domain structure that can be engineered to generate new bacteriocins with enhanced functionalities like activity/stability.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Low Toxicity</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">For generations the commensal bacteria in human body has been employing the bacteriocins to ward off invasions by pathogenic bacteria, hence natural bacteriocins can be expected to be safe to Humans.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Synergy</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The potency of bacteriocin can further be enhanced by combining them with standard of care antibiotics.</p>\r\n      </li>\r\n      \r\n    </ul>\r\n  \r\n</div>\r\n    \r\n<div class=\"abx-white\">\r\n   <div class=\"centerize ctz-md px-3 py-5 text-center anim-hidden fade-in-up\">\r\n     <a href=\"https://carb-x.org/\" target=\"_blank\">\r\n       <img src=\"/wp-content/uploads/2020/10/CARB-X_logo.jpg\" alt=\"carb-x-logo\" style=\"width:300px; margin:0 auto; display:inherit;\" />\r\n     </a>\r\n   </div>\r\n</div>'),
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(22495, 872, 'sections_1_admin_title', 'Lysins Info'),
(22496, 872, '_sections_1_admin_title', 'field_5e865038f6507'),
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(22499, 872, 'sections_1_content', '<div id=\"protein-antibiotic-technology\" class=\"gg-light\">\r\n	<div class=\"centerize ctz-lg px-3 py-5 text-center anim-hidden fade-in-up\">\r\n		<p class=\"gg-japanese-laurel-text\" style=\"font-size:1.4rem; line-height:2;\">Lysins are bacteriophage derived proteins that have antibacterial properties and play important physiological roles during the phage life cycle. These proteins are enzymatic by nature and have either muralytic, proteolytic or hydrolytic activity enabling them to lyse the cell wall of the target bacterium.</p>\r\n	</div>\r\n</div>\r\n\r\n<!-- <div id=\"ectolysin-intro\" class=\"abx-white\">\r\n  <div class=\"centerize ctz-lg px-3 py-5\">\r\n    <div class=\"row\">\r\n      \r\n      <div class=\"col-12 anim-hidden fade-in-up text-center\">\r\n        <h2 class=\"gg-japanese-laurel-text fw-700\">Ectolysins</h2>\r\n        <p class=\"gg-calypso-text\" style=\"line-height:2; font-size:1.4rem;\">Ectolysins help the phage gain entry from outside into the bacterial cell. Endolysins help the phage progeny to burst open &amp; exit the bacterial cell.</p>\r\n        <a href=\"/ectolysin\"><button class=\"gangagen-button\">Learn More</button></a>\r\n      </div>\r\n      \r\n      <div class=\"col-12 col-md-6 anim-hidden fade-in-right text-center\">\r\n        <img src=\"https://via.placeholder.com/250x250/?text=Ectolysin+Image+Goes+Here\" alt=\"ectolysins\" />\r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n</div> -->\r\n\r\n<div id=\"lysin-innovation\" class=\"gg-golden-bell abx-white-text\">\r\n  <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n    <h2 class=\"anim-hidden fade-in-up\">Lysin Innovations</h2>\r\n    <p class=\"anim-hidden fade-in-up\" style=\"line-height:2; font-size:1.4rem;\">GangaGen has used its proprietary PATP to design novel lysin molecules to target both Gram positive and Gram negative pathogens. The most advanced of these is P128 (Staphtame), an Ectolysin that is active on Staphylococci and progressed to clinical trials in humans.</p>\r\n  </div>\r\n</div>'),
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(22562, 874, 'sections_2_content', '<div id=\"ectolysin-advantages\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 py-5\">\r\n    <div class=\"text-left mb-4\">\r\n    	<h2 class=\"fw-900 gg-calypso-text\">Advantages of Ectolysins over Antibiotics</h2>\r\n    </div>\r\n    \r\n    <ul class=\"fa-ul\">\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Rapid Action</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins are rapid acting and cleave the cell wall within a few minutes of contact against antibiotics that only need a few hours to kill the cells.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Specific</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins are very specific to the target bacterial species and hence kill only the target pathogen without affecting the microbiome or the commensal bacterial flora as compared to antibiotics which kill both the pathogens as well as the beneficial bacteria.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Mechanism of Action</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins have novel mode of action- they include enzymatic mechanisms like Muramidase, Glucosaminidase, Amidase or endopeptidase depending upon the cell wall bond targeted by the individual ectolysin.  The availability of a library of enzymatic domains offers the opportunity of protein engineering.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Bactericidal Activity Independence</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Bactericidal activity is not dependent on the metabolic stage of the cell – Ectolysins kill both actively growing as well as stationary phase cells irrespective of the metabolic state. But antibiotics act only on metabolically active cells.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Active on Biofilms</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins are active both on planktonic bacteria &amp; bacterial biofilms as against antibiotics, which act poorly on bacterial biofilms.</p>\r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Low Propensity for Resistance</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Ectolysins cleave essential cell wall chemical bonds, which are highly conserved and omnipresent on the bacterial cell surface; hence the propensity for the development of bacterial resistance is low.</p> \r\n    </ul>\r\n  </div>\r\n</div>\r\n\r\n'),
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(22964, 895, 'sections_1_content', '<div id=\"novel-applications\">\r\n  \r\n  <!-- <div class=\"gg-golden-bell\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      <h2 class=\"anim-hidden fade-in-up gg-golden-bell-text fw-900\">Novel Applications: GBPL\'s Efforts</h2>\r\n      <p class=\"abx-white-text anim-hidden fade-in-up text-center\" style=\"font-size:1.4rem; line-height:2;\">Phages can be used to control undesirable bacteria in various settings where bacteria may cause disease, contamination, disturbance or imbalance in natural microbiomes, or other problems. Gangagen has also used phages to tackle environment related challenges.</p>\r\n    </div>\r\n  </div> -->\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      \r\n      <div class=\"text-center\">\r\n        <h2 class=\"anim-hidden fade-in-up gg-golden-bell-text fw-900\">Applications in Poultry</h2>\r\n        <p class=\"anim-hidden fade-in-up gg-golden-bell-text\" style=\"font-size:1.4rem; line-height:2;\">GBPL has developed a cocktail of lytic phages to control <em>Salmonella</em> infection in chicken. The company has isolated a number of phages and identified 3 phages that are capable of killing most of the <em>Salmonella</em> isolates present in the poultry field. GBPL scientists have characterized these phages and also conducted a field trial to establish efficacy of the phage cocktail and to improve overall health and FCR (Feed Conversion Ratio) in the birds. This product is available for commercial evaluation and marketing.</p>\r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-light\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      \r\n      <div class=\"text-center\">\r\n        <h2 class=\"anim-hidden fade-in-up gg-calypso-text fw-900\">Other Areas Of Interest</h2>\r\n        <p class=\"anim-hidden fade-in-up gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">GBPL has explored the use of bacteriophages in tackling <em>Vibrio harveyi</em> infections in aquaculture industry and isolated phages that work on these bacteria. The company is open for collaborative approach to develop this as a product. In addition, GBPL has worked on isolating phages that can kill sulphate reducing bacteria responsible for corrosion of oil pipelines and establishing a method of testing them for efficacy. </p>\r\n        <p class=\"anim-hidden fade-in-up gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">Any industrial set up looking for a phage based, eco-friendly solution to combat bacterial burden, may contact us for a mutually beneficial research programs.</p>\r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-calypso abx-white-text\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n    	<h2 class=\"fw-900 anim-hidden fade-in-down animated visible fadeInDown full-visible\">For More Information:</h2>\r\n    	<div class=\"text-center\">\r\n    		<a href=\"mailto:info@gangagen\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Email</button></a>\r\n    		<a href=\"/contact\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Contact Form</button></a>\r\n    	</div>\r\n    </div>\r\n  </div>\r\n  \r\n</div>\r\n'),
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(23199, 899, 'sections_3_admin_title', 'Ectolysins Against Gram Positive and Negative Bacteria'),
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(23238, 900, 'sections_1_content', '<div id=\"p128\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 py-5\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12\">\r\n        <h2 class=\"gg-japanese-laurel-text fw-900 text-center\">How Does Ectolysin P128 Work?</h2>\r\n        <p class=\"gg-japanese-laurel-text\" style=\"font-size:1.4rem; line-height:2;\">Ectolysin P128, GangaGen’s lead ectolysin is a recombinant, chimeric protein that comprises of two functionally distinct domains. The catalytic domain is a muralytic enzyme and the binding domain specifically interacts with the pentaglycine bridge connecting the D-Ala-D-Ala moieties of adjacent peptidoglycan strands. Functionally, P128 is an endopeptidase and its enzymatic action on the staphylococcal peptidoglycan results in the cleavage of the specifc peptide linkages. This leads to the degradation of the cell wall, followed by osmotic lysis and rapid death of the bacterium. P128 targets both coagulase positive and coagulase negative Staphylococci.</p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n</div>\r\n    \r\n<div id=\"mechanism-of-action\" class=\"abx-white\">\r\n  <div class=\"centerize ctz-lg px-3 pt-5\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 col-md-6 anim-hidden fade-in-left\">\r\n        <img src=\"/wp-content/uploads/2020/09/4.-P128-Mechanism-of-Action.jpg\" alt=\"p128\" />\r\n      </div>\r\n      <div class=\"col-12 col-md-6 anim-hidden fade-in-right\">\r\n        <h2 class=\"gg-japanese-laurel-text fw-900\">Mechanism of Action</h2>\r\n        <p class=\"gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">P128 has a novel mechanism of action and has been proven to be very effective both <em>in vitro</em> &amp; <em>in vivo</em> against multidrug resistant pathogens like Methicillin Resistant <em>Staphylococcus aureus</em> (MRSA), Vancomycin Resistant <em>Staphylococcus aureus</em> (VRSA) and Daptomycin Resistant <em>Staphylococcus aureus</em> (DRSA).</p> \r\n      </div>\r\n    </div>\r\n  </div>\r\n</div>\r\n    \r\n<div id=\"p128-manufacturing\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 pt-5\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 anim-hidden fade-in-up text-center\">\r\n        <h2 class=\"gg-japanese-laurel-text fw-900\">Scalable Manufacturing Process</h2>\r\n        <p class=\"gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">GangaGen has successfully developed the manufacturing process for large scale production of P128 to meet the regulatory standards for clinical studies. P128 formulated as a gel for topical use has been tested in a first-in-human clinical trial, a Phase I/IIA study directed towards treatment of nasal carriage of <em>S. aureus</em>.</p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n</div>\r\n\r\n<!-- <div id=\"p128-chart\" class=\"abx-white\">\r\n  <div class=\"px-3 py-5\">\r\n    <img class=\"anim-hidden fade-in-up\" src=\"/wp-content/uploads/2020/09/6.-P128-banner_final-scaled.jpg\" alt=\"p128-chart\" />\r\n  </div>\r\n</div> -->\r\n\r\n<!-- <div id=\"p128-quote\" style=\"padding:10% 2rem; background:linear-gradient(rgba(0,0,0,0.4),rgba(0,0,0,0.4)), url(\'/wp-content/uploads/2020/09/gangagen-007.jpg\'); background-attachment:fixed; background-size:cover; background-repeat:no-repeat;\">\r\n  <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n    <p class=\"abx-white-text fw-700 anim-hidden zoom-in\" style=\"font-size:1.4rem; line-height:2;\"><span class=\"quot\" style=\"display:block;\"><i class=\"fa fa-3x fa-quote-left\"></i></span><em>In 15 European countries more than 10% of blood-stream Staphylococcus aureus infections are caused by methicillin-resistant strains (MRSA), with several of these countries seeing resistance rates closer to 50%.</em><span class=\"quot\" style=\"display:block;\"><i class=\"fa fa-4x fa-quote-right\"></i></span></p>\r\n  </div>\r\n</div> -->\r\n\r\n<div id=\"p128-innovation\" class=\"gg-light gg-calypso-text\">\r\n  <div class=\"centerize ctz-md px-3 py-5 text-center\">\r\n     <h2 class=\"fw-900 anim-hidden fade-in-down\">P128 Clinical Trial</h2>\r\n  	 <p class=\"anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">GBPL advanced its candidate compound into human clinical trials for the decolonization of <em>Staphylococcus aureus</em> from human nares.</p>    \r\n  </div>\r\n</div>\r\n    \r\n<div id=\"p128-innovation\" class=\"gg-calypso gg-light-text\">\r\n  <div class=\"centerize ctz-md px-3 py-5 text-center\">\r\n     <h2 class=\"fw-900 anim-hidden fade-in-down\">Intravenous Treatment</h2>\r\n  	 <p class=\"anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">GBPL is also advancing Ectolysin P128 for intravenous treatment of bacteremia caused by Staphylococcus Species.</p>    \r\n  </div>\r\n</div>\r\n\r\n\r\n'),
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(23272, 901, 'sections_1_admin_title', 'Introduction'),
(23273, 901, '_sections_1_admin_title', 'field_5e865038f6507'),
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(23276, 901, 'sections_1_content', '<div id=\"novel-applications\">\r\n  \r\n  <!-- <div class=\"gg-golden-bell\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      <h2 class=\"anim-hidden fade-in-up gg-golden-bell-text fw-900\">Novel Applications: GBPL\'s Efforts</h2>\r\n      <p class=\"abx-white-text anim-hidden fade-in-up text-center\" style=\"font-size:1.4rem; line-height:2;\">Phages can be used to control undesirable bacteria in various settings where bacteria may cause disease, contamination, disturbance or imbalance in natural microbiomes, or other problems. Gangagen has also used phages to tackle environment related challenges.</p>\r\n    </div>\r\n  </div> -->\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      \r\n      <div class=\"text-center\">\r\n        <h2 class=\"anim-hidden fade-in-up gg-golden-bell-text fw-900\">Applications in Poultry</h2>\r\n        <p class=\"anim-hidden fade-in-up gg-golden-bell-text\" style=\"font-size:1.4rem; line-height:2;\">GBPL has developed a cocktail of lytic phages to control <em>Salmonella</em> infection in chicken. The company has isolated a number of phages and identified 3 phages that are capable of killing most of the <em>Salmonella</em> isolates present in the poultry industry. GBPL scientists have characterized these phages and also conducted a field trial to establish efficacy of the phage cocktail and to improve overall health and FCR (Feed Conversion Ratio) in the birds. This product is available for commercial evaluation and marketing.</p>\r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-light\">\r\n    <div class=\"centerize ctz-md px-3 py-5\">\r\n      \r\n      <div class=\"text-center\">\r\n        <h2 class=\"anim-hidden fade-in-up gg-calypso-text fw-900\">Other Areas Of Interest</h2>\r\n        <p class=\"anim-hidden fade-in-up gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">GBPL has explored the use of bacteriophages in tackling <em>Vibrio harveyi</em> infections in aquaculture industry and isolated phages that work on these bacteria. The company is open for collaborative approach to develop this as a product. In addition, GBPL has worked on isolating phages that can kill sulphate reducing bacteria responsible for corrosion of oil pipelines and establishing a method of testing them for efficacy. </p>\r\n        <p class=\"anim-hidden fade-in-up gg-calypso-text\" style=\"font-size:1.4rem; line-height:2;\">Any industrial set up looking for a phage based, eco-friendly solution to combat bacterial burden, may contact us for a mutually beneficial research programs.</p>\r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-calypso abx-white-text\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n    	<h2 class=\"fw-900 anim-hidden fade-in-down animated visible fadeInDown full-visible\">For More Information:</h2>\r\n    	<div class=\"text-center\">\r\n    		<a href=\"mailto:info@gangagen\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Email</button></a>\r\n    		<a href=\"/contact\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Contact Form</button></a>\r\n    	</div>\r\n    </div>\r\n  </div>\r\n  \r\n</div>\r\n'),
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(23312, 902, 'sections_1_content', '<div id=\"ectolysins-against-gram-postitive-bacteria\" class=\"gg-light\">\r\n  <div class=\"centerize ctz-lg px-3 py-5\">\r\n    <h2 class=\"text-center gg-japanese-laurel-text fw-900 anim-hidden fade-in-down\">Ectolysins against Staphylococcus</h2>\r\n	<p class=\"gg-calypso-text text-center anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">Ectolysin P128, GangaGen’s lead molecule is a chimeric recombinant anti-staphylococcal protein that targets both coagulase positive and coagulase negative Staphylococci.</p> \r\n    <p class=\"gg-calypso-text text-center anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">P128 has a novel mechanism of action and rapidly kills Staphylococci.</p>\r\n	<p class=\"gg-calypso-text text-center anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">It is proven to be very effective both <em>in vitro &amp; in vivo</em> against multidrug resistant pathogens like Methicillin Resistant <em>Staphylococcus</em> aureus (MRSA), Vancomycin Resistant <em>Staphylococcus aureus</em> (VRSA) and Daptomycin Resistant <em>Staphylococcus aureus</em> (DRSA). GangaGen has completed Phase I/IIA studies with P128 for ‘nasal decontamination\' of <em>S. aureus</em> from human nares.</p>	\r\n  </div>\r\n</div>\r\n\r\n<div class=\"gg-japanese-laurel gg-light-text\" style=\"border-bottom:solid 3px var(--gg-light);\">\r\n  <div class=\"centerize ctz-md text-center px-3 py-5\">\r\n    <h2 class=\"fw-900 text-center anim-hidden fade-in-down\">Ectolysins against Enterococcus</h2>\r\n	<p class=\"anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">GangaGen has used PATP to discover and engineer novel ectolysins suitable for multiple applications.</p>\r\n  </div>\r\n</div>'),
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(23348, 903, 'sections_1_content', '<div id=\"protein-antibiotic-technology\" class=\"gg-calypso\">\r\n	<div class=\"centerize ctz-lg px-3 py-5 text-center anim-hidden fade-in-up\">\r\n        <h2 class=\"abx-white-text fw-900\">What are Bacteriocins?</h2>\r\n		<p class=\"abx-white-text\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins are a diverse family of protein molecules produced by many bacterial species, that exhibit antibacterial activity. Bacteria produce these bacteriocins to eliminate competition from other closely related bacteria. Bacteriocins are naturally occurring antibacterial proteins that can be developed as potent antibiotics.</p>\r\n	</div>\r\n</div>\r\n      	\r\n      \r\n\r\n'),
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(23370, 903, 'sections_2_admin_title', 'Gram Negative Bacteriocins'),
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(23374, 903, 'sections_2_content', '<div id=\"gram-negative-bacteriocins\">\r\n  \r\n  <div class=\"gg-japanese-laurel abx-white-text text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 anim-hidden fade-in-up\">\r\n      <h2 class=\"fw-900\">Gram Negative Bacteriocins</h2>\r\n      <p style=\"line-height:2; font-size:1.4rem;\">Bacteriocins from Gram negative bacteria are broadly classified into 3 types based on their size as:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n\r\n      <div class=\"row\">\r\n        <!-- /wp-content/uploads/2020/09/2a.-Peptide-Bacteriocins.jpg.jpg -->\r\n        <div class=\"col-12 col-md-4 text-center anim hidden fade-in-left\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/10/2a-Peptide-Bacteriocins.jpg.jpg\" alt=\"peptide-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Peptide Bacteriocins</h3>\r\n          <p>Peptide Bacteriocins like microcins of less than 10 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-up\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/09/2b.-Colicins-Like-Bacteriocins.jpg-e1600372580990.jpg\" alt=\"colicin-like-bacteriocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Colicin-Like Bacteriocins (CLB)</h3>\r\n          <p>Colicin-Like Bacteriocins (CLB) of 25 – 80 kDa size</p>\r\n        </div>\r\n        \r\n        <div class=\"col-12 col-md-4 text-center anim-hidden fade-in-right\">\r\n          <img style=\"height:190px;\" class=\"mb-3\" src=\"/wp-content/uploads/2020/10/Lambda-Ur_Tail_model-scaled.jpg\" alt=\"tailocins\" />\r\n          <h3 class=\"gg-japanese-laurel-text mb-3\">Tailocins</h3>\r\n          <p>Tailocins are high molecular size bacteriocins that resemble the tail structures of bacteriophages </p\r\n        </div>\r\n        \r\n      </div>\r\n      \r\n    </div>\r\n  </div>\r\n  \r\n   <div id=\"how-and-mechanisms\" class=\"px-0 py-0\" style=\"border-top:solid 8px var(--gg-calypso);\">\r\n    <div class=\"row\">\r\n      <div class=\"col-12 col-md-6 abx-white py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-calypso-text fw-900 anim-hidden fade-in-left\">How Does It Work?</h2>\r\n        	<p class=\"gg-calypso-text anim-hidden fade-in-left\" style=\"font-size:1.4rem; line-height:2;\">The CLBs entry into the bacterial cell is mediated through its interaction with cell-surface receptors, and thus conferring both specificity and selectivity. The Bacteriocin producing bacterium is protected from its own action by an immunity protein co-expressed with it.</p>\r\n        </div>\r\n      </div>\r\n      <div class=\"col-12 col-md-6 gg-light py-5 text-center\">\r\n        <div class=\"centerize ctz-sm\">\r\n        	<h2 class=\"gg-japanese-laurel-text fw-900 anim-hidden fade-in-right\">Mechanism of Action</h2>\r\n        	<p class=\"gg-japanese-laurel-text anim-hidden fade-in-right\" style=\"font-size:1.4rem; line-height:2;\">The mechanism of killing is through multiple modes such as cell wall damage, cell membrane damage, interfering in metabolic pathways, and DNase or RNase activities.</p>\r\n        </div>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages-header\" class=\"gg-calypso text-center\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n    	<h2 class=\"fw-900 abx-white-text anim-hidden fade-in-up\">Advantages of Bacteriocins</h2>\r\n    	<p class=\"abx-white-text anim-hidden fade-in-up\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins offer several advantages over antibiotics making them attractive starting points for developing anti-bacterial agents:</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div id=\"bacteriocin-advantages\" class=\"gg-light\">\r\n   <div class=\"centerize ctz-md px-3 py-5\">\r\n    \r\n    <ul class=\"fa-ul\">\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Specific</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Their specificity offers a targeted approach and kills only the target pathogen, without damaging the commensal human microbiota or microbiome.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Resistance Development</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The Bacteriocins have a unique mode of action and hence there is no primed resistance in the bacterial community.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Selective</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">Bacteriocins enter the bacterial cell through specific receptors which are absent on eukaryotic cells and hence are very selective agents.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Modular Architecture</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The colicin like bacteriocins (CLB) have modular domain structure that can be engineered to generate new bacteriocins with enhanced functionalities like activity/stability.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Low Toxicity</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">For generations the commensal bacteria in human body has been employing the bacteriocins to ward off invasions by pathogenic bacteria, hence natural bacteriocins can be expected to be safe to Humans.</p>\r\n      </li>\r\n      \r\n      <li class=\"anim-hidden fade-in-left mb-4\"><span class=\"fa-li\"><i class=\"fa fa-check gg-check\"></i></span> \r\n        <h3 class=\"fw-900 gg-calypso-text ml-3\">Synergy</h3> \r\n        <p class=\"ml-3\" style=\"font-size:1.4rem; line-height:2;\">The potency of bacteriocin can further be enhanced by combining them with standard of care antibiotics.</p>\r\n      </li>\r\n      \r\n    </ul>\r\n  \r\n</div>\r\n    \r\n<div class=\"abx-white\">\r\n   <div class=\"centerize ctz-md px-3 py-5 text-center anim-hidden fade-in-up\">\r\n     <a href=\"https://carb-x.org/\" target=\"_blank\">\r\n       <img src=\"/wp-content/uploads/2020/10/CARB-X_logo.jpg\" alt=\"carb-x-logo\" style=\"width:300px; margin:0 auto; display:inherit;\" />\r\n     </a>\r\n   </div>\r\n</div>'),
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(23777, 933, 'sections_1_content', '<div id=\"bacteriophage-pipeline\">\r\n  \r\n  <div class=\"gg-japanese-laurel abx-white-text\">\r\n    <div class=\"centerize ctz-md px-3 py-5 text-center\">\r\n      <h2 class=\"anim-hidden fade-in-up\">Detection of adventitious phage contamination in Bacterial cell banks:</h2>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-light\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n      <div>\r\n        <p class=\"gg-japanese-laurel-text anim-hidden fade-in-up\" style=\"line-height:2; font-size:1.4rem;\">GangaGen, with expertise in phage biology offers customized bacteriophage testing services to determine the presence or absence of phage contaminants in bacterial cell banks or production cells. Our team has more than fifteen years of experience and provides high quality phage testing services in tune with regulatory requirements in a timely manner. We offer both lytic and lysogenic phage detection for <em>E. coli</em> cell banks. Currently this service is offered as a Non-GLP activity.</p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n      <p class=\"gg-calypso-text anim-hidden fade-in-up\" style=\"line-height:2; font-size:1.4rem;\">The commercial production of recombinant biologicals and therapeutics is an important outcome of modern biotechnology. Selecting an ideal host bacterium to produce specific protein of interest is an important step in developing a production process. Widespread use of <em>E. coli</em> and other bacterial systems in biotechnology has led to the development of many different strains/cell lines. The process developed in production of therapeutics has to be taken to industrial scale to get viable industrial production mainly through fermentation technology.</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-light\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n      <div>\r\n        <p class=\"gg-japanese-laurel-text anim-hidden fade-in-up\" style=\"line-height:2; font-size:1.4rem;\">The starting material for manufacturing includes a well characterized bacterial culture, known to be free from bacteriophage and is capable of expressing the protein product of interest in good measure. Production host bacterial cell “seed lot” system is used by manufacturers to assure identity and purity of the starting raw material viz., production host culture. A cell seed lot/research cell bank consists of aliquots of a single culture from where the <strong><em>“Master Cell Bank” (MCB)</em></strong> and <strong><em>“Working Cell Bank” (WCB)</em></strong> are derived. A well-characterized cell bank assures lot-to-lot consistency of the product. Regulatory agencies such as USFDA, EMEA require MCBs to adhere to ICH guidelines which emphasizes on characterization and testing to establish identity, purity and genetic stability of the cell line. A phage contaminated cell bank cannot be termed as <em>\"stable\"</em> as it may not generate the required cell density in a sustainable fashion during the fermentation process because of contaminating phages. Thus, it becomes essential to establish absence of phages in cell banks by conducting the prescribed battery of tests. </p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n      <div>\r\n        <h2 class=\"gg-calypso-text anim-hidden fade-in-up\">Bacteriophage Detection Services</h2>\r\n        <p class=\"gg-calypso-text anim-hidden fade-in-up\" style=\"line-height:2; font-size:1.4rem;\">We offer both lytic and lysogenic phage detection for <em>E. coli</em> cell banks. This service offered by GangaGen is an ISO-9001:2015 certifid activity.</p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-calypso abx-white-text\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n      <h2 class=\"fw-900 anim-hidden fade-in-down animated visible fadeInDown full-visible\">For More Information:</h2>\r\n      <div class=\"text-center\">\r\n    	<a href=\"mailto:info@gangagen\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Email</button></a>\r\n    	<a href=\"/contact\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Contact Form</button></a>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n</div>'),
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(23813, 935, 'sections_1_content', '<div id=\"bacteriophage-pipeline\">\r\n  \r\n  <div class=\"gg-japanese-laurel abx-white-text\">\r\n    <div class=\"centerize ctz-md px-3 py-5 text-center\">\r\n      <h2 class=\"anim-hidden fade-in-up\">Detection of adventitious phage contamination in Bacterial cell banks:</h2>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-light\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n      <div>\r\n        <p class=\"gg-japanese-laurel-text anim-hidden fade-in-up\" style=\"line-height:2; font-size:1.4rem;\">GangaGen, with expertise in phage biology offers customized bacteriophage testing services to determine the presence or absence of phage contaminants in bacterial cell banks or production cells. Our team has more than fifteen years of experience and provides high quality phage testing services in tune with regulatory requirements in a timely manner. We offer both lytic and lysogenic phage detection for <em>E. coli</em> cell banks. Currently this service is offered as a Non-GLP activity.</p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n      <p class=\"gg-calypso-text anim-hidden fade-in-up\" style=\"line-height:2; font-size:1.4rem;\">The commercial production of recombinant biologicals and therapeutics is an important outcome of modern biotechnology. Selecting an ideal host bacterium to produce specific protein of interest is an important step in developing a production process. Widespread use of <em>E. coli</em> and other bacterial systems in biotechnology has led to the development of many different strains/cell lines. The process developed in production of therapeutics has to be taken to industrial scale to get viable industrial production mainly through fermentation technology.</p>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-light\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n      <div>\r\n        <p class=\"gg-japanese-laurel-text anim-hidden fade-in-up\" style=\"line-height:2; font-size:1.4rem;\">The starting material for manufacturing includes a well characterized bacterial culture, known to be free from bacteriophage and is capable of expressing the protein product of interest in good measure. Production host bacterial cell “seed lot” system is used by manufacturers to assure identity and purity of the starting raw material viz., production host culture. A cell seed lot/research cell bank consists of aliquots of a single culture from where the <strong><em>“Master Cell Bank” (MCB)</em></strong> and <strong><em>“Working Cell Bank” (WCB)</em></strong> are derived. A well-characterized cell bank assures lot-to-lot consistency of the product. Regulatory agencies such as USFDA, EMEA require MCBs to adhere to ICH guidelines which emphasizes on characterization and testing to establish identity, purity and genetic stability of the cell line. A phage contaminated cell bank cannot be termed as <em>\"stable\"</em> as it may not generate the required cell density in a sustainable fashion during the fermentation process because of contaminating phages. Thus, it becomes essential to establish absence of phages in cell banks by conducting the prescribed battery of tests. </p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"abx-white\">\r\n    <div class=\"centerize ctz-lg px-3 py-5\">\r\n      <div>\r\n        <h2 class=\"gg-calypso-text anim-hidden fade-in-up\">Bacteriophage Detection Services</h2>\r\n        <p class=\"gg-calypso-text anim-hidden fade-in-up\" style=\"line-height:2; font-size:1.4rem;\">We offer both lytic and lysogenic phage detection for <em>E. coli</em> cell banks. This service offered by GangaGen is an ISO-9001:2015 certifid activity.</p>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n  <div class=\"gg-calypso abx-white-text\">\r\n    <div class=\"centerize ctz-lg px-3 py-5 text-center\">\r\n      <h2 class=\"fw-900 anim-hidden fade-in-down animated visible fadeInDown full-visible\">For More Information:</h2>\r\n      <div class=\"text-center\">\r\n    	<a href=\"mailto:info@gangagen\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Email</button></a>\r\n    	<a href=\"/contact\"><button class=\"gangagen-button-clear anim-hidden fade-in-up animated visible fadeInUp full-visible\">Contact Form</button></a>\r\n      </div>\r\n    </div>\r\n  </div>\r\n  \r\n</div>'),
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